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All Projects → YuLab-SMU → DOSE

YuLab-SMU / DOSE

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😷 Disease Ontology Semantic and Enrichment analysis

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semantic-similaritydisease-ontologyenrichment-analysis

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DOSE: Disease Ontology Semantic and Enrichment analysis

Bioc codecov

Project Status: Active - The project has reached a stable, usable state and is being actively developed. platform Build Status Linux/Mac Travis Build Status AppVeyor Build Status

This package implements five methods proposed by Resnik, Schlicker, Jiang, Lin and Wang respectively for measuring semantic similarities among DO terms and gene products. Enrichment analyses including hypergeometric model and gene set enrichment analysis are also implemented for discovering disease associations of high-throughput biological data.

For details, please visit https://yulab-smu.top/biomedical-knowledge-mining-book/.

✍️ Authors

Guangchuang YU https://yulab-smu.top

School of Basic Medical Sciences, Southern Medical University

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Please cite the following article when using DOSE:

G Yu, LG Wang, GR Yan, QY He. DOSE: an R/Bioconductor package for Disease Ontology Semantic and Enrichment analysis. Bioinformatics 2015, 31(4):608-609.

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