Janggu Deep learning infrastructure for bioinformatics
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FqtoolsAn efficient FASTQ manipulation suite
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ClairvoyanteClairvoyante: a multi-task convolutional deep neural network for variant calling in Single Molecule Sequencing
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UgeneUGENE is free open-source cross-platform bioinformatics software
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Dgl LifesciPython package for graph neural networks in chemistry and biology
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BiofastBenchmarking programming languages/implementations for common tasks in Bioinformatics
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Soapdenovo2Next generation sequencing reads de novo assembler.
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CgrangesA C/C++ library for fast interval overlap queries (with a "bedtools coverage" example)
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SurvivorToolset for SV simulation, comparison and filtering
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TaxonkitA Practical and Efficient NCBI Taxonomy Toolkit
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ScdeR package for analyzing single-cell RNA-seq data
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IndraINDRA (Integrated Network and Dynamical Reasoning Assembler) is an automated model assembly system interfacing with NLP systems and databases to collect knowledge, and through a process of assembly, produce causal graphs and dynamical models.
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MinigraphProof-of-concept seq-to-graph mapper and graph generator
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GenomicsA collection of scripts and notes related to genomics and bioinformatics
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PysradbPackage for fetching metadata and downloading data from SRA/ENA/GEO
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SmudgeplotInference of ploidy and heterozygosity structure using whole genome sequencing data
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WgsimReads simulator
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AribaAntimicrobial Resistance Identification By Assembly
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NextflowA DSL for data-driven computational pipelines
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Raxml NgRAxML Next Generation: faster, easier-to-use and more flexible
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FastqtFastQC port to Qt5: A quality control tool for high throughput sequence data.
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ArtemisArtemis is a free genome viewer and annotation tool that allows visualization of sequence features and the results of analyses within the context of the sequence, and its six-frame translation
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BioBioinformatics library for .NET
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RoaryRapid large-scale prokaryote pan genome analysis
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SwarmA robust and fast clustering method for amplicon-based studies
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Awesome Single CellCommunity-curated list of software packages and data resources for single-cell, including RNA-seq, ATAC-seq, etc.
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DecontamSimple statistical identification and removal of contaminants in marker-gene and metagenomics sequencing data
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ClusterflowA pipelining tool to automate and standardise bioinformatics analyses on cluster environments.
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MrbayesMrBayes is a program for Bayesian inference and model choice across a wide range of phylogenetic and evolutionary models. For documentation and downloading the program, please see the home page:
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Obofoundry.github.ioMetadata and website for the Open Bio Ontologies Foundry Ontology Registry
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Goleftgoleft is a collection of bioinformatics tools distributed under MIT license in a single static binary
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TruvariStructural variant toolkit for VCFs
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Hts Nimnim wrapper for htslib for parsing genomics data files
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Awesome 10x GenomicsList of tools and resources related to the 10x Genomics GEMCode/Chromium system
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KaryoploterkaryoploteR - An R/Bioconductor package to plot arbitrary data along the genome
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EdamontologyEDAM is an ontology of bioinformatics types of data including identifiers, data formats, operations and topics.
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SplatterSimple simulation of single-cell RNA sequencing data
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SvtyperBayesian genotyper for structural variants
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AnndataAnnotated data.
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Biosequences.jlBiological sequences for the julia language
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Somalierfast sample-swap and relatedness checks on BAMs/CRAMs/VCFs/GVCFs... "like damn that is one smart wine guy"
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Fastq.bioAn interactive web tool for quality control of DNA sequencing data
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SequenceserverIntuitive local web frontend for the BLAST bioinformatics tool
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PlassProtein-Level ASSembler (PLASS): sensitive and precise protein assembler
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SarekDetect germline or somatic variants from normal or tumour/normal whole-genome or targeted sequencing
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StartappThe START App: R Shiny Transcriptome Analysis Resource Tool
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AfterqcAutomatic Filtering, Trimming, Error Removing and Quality Control for fastq data
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Coursera SpecializationsSolutions to assignments of Coursera Specializations - Deep learning, Machine learning, Algorithms & Data Structures, Image Processing and Python For Everybody
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Krakenuniq🐙 KrakenUniq: Metagenomics classifier with unique k-mer counting for more specific results
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GlobalbioticinteractionsGlobal Biotic Interactions provides access to existing species interaction datasets
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RibbonA genome browser that shows long reads and complex variants better
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ScgenSingle cell perturbation prediction
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Bedops🔬 BEDOPS: high-performance genomic feature operations
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Awesome Cancer Variant DatabasesA community-maintained repository of cancer clinical knowledge bases and databases focused on cancer variants.
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IntermineA powerful open source data warehouse system
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GrapheinProtein Graph Library
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RagooFast Reference-Guided Scaffolding of Genome Assembly Contigs. RagTag, the successor to RaGOO, is now available here: https://github.com/malonge/RagTag
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HicexplorerHiCExplorer is a powerful and easy to use set of tools to process, normalize and visualize Hi-C data.
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