alevin-fry🐟 🔬🦀 alevin-fry is an efficient and flexible tool for processing single-cell sequencing data, currently focused on single-cell transcriptomics and feature barcoding.
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kmer-homology-paperManuscript for functional prediction of transcriptomic “dark matter” across species
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PandoMultiome GRN inference.
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scCATCHAutomatic Annotation on Cell Types of Clusters from Single-Cell RNA Sequencing Data
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diffxpyDifferential expression analysis for single-cell RNA-seq data.
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scadenDeep Learning based cell composition analysis with Scaden.
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NebulosaR package to visualize gene expression data based on weighted kernel density estimation
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cnaCovarying neighborhood analysis (CNA) is a method for finding structure in- and conducting association analysis with multi-sample single-cell datasets.
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SOTSingle-cell Orientation Tracing
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pychopperA tool to identify, orient, trim and rescue full length cDNA reads
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DEcodeA prediction model for differential gene expression (DE) based on genome-wide regulatory interactions
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GCModellerGCModeller: genomics CAD(Computer Assistant Design) Modeller system in .NET language
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SpiceMixspatial transcriptome, single cell
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MERlinMERlin is an extensible analysis pipeline applied to decoding MERFISH data
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celltypistA tool for semi-automatic cell type annotation
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kallistobustoolskallisto | bustools workflow for pre-processing single-cell RNA-seq data
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pipeline-pinfish-analysisPipeline for annotating genomes using long read transcriptomics data with pinfish
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D3EDiscrete Distributional Differential Expression
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scLearnscLearn:Learning for single cell assignment
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squidpySpatial Single Cell Analysis in Python
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SCopeLoomRR package (compatible with SCope) to create generic .loom files and extend them with other data e.g.: SCENIC regulons, Seurat clusters and markers, ...
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TransPiTransPi – a comprehensive TRanscriptome ANalysiS PIpeline for de novo transcriptome assembly
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GLUEGraph-linked unified embedding for single-cell multi-omics data integration
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mgatkmgatk: mitochondrial genome analysis toolkit
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cellrangerRkitNon-official Git repository for R package cellrangerRkit (currently not available elsewhere; I'm not affiliated with 10x)
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EDS💡 💾 💽 A simple, intuitive and Efficient single cell binary Data Storage format
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immunarch🧬 Immunarch by ImmunoMind: R Package for Fast and Painless Exploration of Single-cell and Bulk T-cell/Antibody Immune Repertoires
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dammitjust annotate it, dammit!
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SINCERAAn R implementation of the SINCERA pipeline for single cell RNA-seq profiling analysis
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bapBead-based single-cell atac processing
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paccmann rlCode pipeline for the PaccMann^RL in iScience: https://www.cell.com/iscience/fulltext/S2589-0042(21)00237-6
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IsoQuantReference-based transcript discovery from long RNA read
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scedarSingle-cell exploratory data analysis for RNA-Seq
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CUT-RUNTools-2.0CUT&RUN and CUT&Tag data processing and analysis
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MERINGUEcharacterizing spatial gene expression heterogeneity in spatially resolved single-cell transcriptomics data with nonuniform cellular densities
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EmptyDrops2017Code for the empty droplet and cell detection project from the HCA Hackathon.
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crop-seqData analysis scripts for Datlinger et. al, 2017 (doi:10.1038/nmeth.4177)
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scTCRseqProcessing of single cell RNAseq data for the recovery of TCRs in python
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scarfToolkit for highly memory efficient analysis of single-cell RNA-Seq, scATAC-Seq and CITE-Seq data. Analyze atlas scale datasets with millions of cells on laptop.
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vitessceRR API and htmlwidget for Vitessce
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VoxHuntVoxHunt: Resolving human brain organoid heterogeneity through single-cell genomic comparison to spatial brain maps
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iDEADifferential expression (DE); gene set Enrichment Analysis (GSEA); single cell RNAseq studies (scRNAseq)
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dynmethodsA collection of 50+ trajectory inference methods within a common interface 📥📤
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gchromVARCell type specific enrichments using finemapped variants and quantitative epigenetic data
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SCOPE-toolsSingle-Cell Omics Preparation Entity Tools
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scABCNo description or website provided.
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scrattch.visscRNA-seq data visualization from scrattch
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dee2Digital Expression Explorer 2 (DEE2): a repository of uniformly processed RNA-seq data
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cellsnp-liteEfficient genotyping bi-allelic SNPs on single cells
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sintoTools for single-cell data processing
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metacellMetacell - Single-cell mRNA Analysis
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piscesPISCES is a pipeline for rapid transcript quantitation, genetic fingerprinting, and quality control assessment of RNAseq libraries using Salmon.
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GeneTonicEnjoy your transcriptomic data and analysis responsibly - like sipping a cocktail
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anndata2riConvert between AnnData and SingleCellExperiment
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